Police in Perth say they have identified another two people who have lost large sums of money from romance scams operating out of Africa.

Police recently issued an alert about the scams after the body of 67-year-old Jetta Jacobs, from Wagin, was found in a villa in Johannesburg.

The grandmother had travelled to the city to meet Jesse Omokoh, 28, after sending him more than $100,000.

Police in South Africa initially believed her death was suicide but are now treating it as a possible homicide.

Fraud Squad detectives say they have identified a Perth businessman who has sent $500,000 to the scammers and a woman from Melbourne who has lost $100,000.

Detective Sergeant Rob Martin says it took police a long time to convince both people they were the victims of a scam.