Three boys are expected to appear in an Oklahoma court on first degree murder charges for the drive-by shooting of Australian baseballer Chris Lane.

The boys - aged 15, 16 and 17 - are scheduled to be arraigned at the Stephens County Courthouse on Monday afternoon (about 5am Tuesday AEST).

If convicted of first degree murder, the boys could be sentenced to death.

Mr Lane, who grew up in Melbourne's north, died on Friday afternoon after he left his girlfriend Sarah Harper's home for a jog in a quiet, upper-class area of the small city of Duncan, Oklahoma.

Police allege the accused killers followed Mr Lane, shot him in the back and sped off in a random drive-by, before heading to another house with plans to kill again.

Mr Lane, 22, had been in the US on a baseball sports scholarship with East Central University (ECU) as the team's catcher.

Witnesses saw him stumble across the road and then go down on his knees before struggling to a drainage area at the side of the road.

Mr Lane's father, Peter, described his son's death as "senseless".