Jason Day's opening round at the Tour Championship will be his first at East Lake Golf Club for two years but the world No. 16 says he'll be ready.

Struck down by an energy zapping sinus infection midway through last week's BMW Championship in Chicago the 25-year-old was forced to limit his preparation in Atlanta, taking Tuesday off and only practicing on the range and practice greens Wednesday.

But the Queenslander says the lack of practice rounds won't be a factor, instead relying on his knowledge from his 2010 and 2011 appearances where he was tied 17th and sixth respectively.

More importantly, the infection is now under control and on its way out of his system.

"I'm felling much better. I'm still a little blocked up in the ears and nose but I feel good," Day said.

"I took yesterday off which was nice and got some rest and I'm still taking it easy to keep the energy stores up."

Despite the illness Day managed to finish tied fourth last week and comes into the season ending 30-man event excited about his game. With only the 2010 Byron Nelson Championship in his trophy cabinet he sees the event as a golden opportunity to add some more silverware.

"I feel close to 100 times better than I did last week so that's good. I feel like I am in a really good place mentally and my game is good," he said.

"To win on a stage like this against the hottest players on the PGA Tour for the year would obviously be amazing.

"It would give you not only the exemptions and the money but mainly the confidence it would garner going into the future."

As the 14th seed Day knows he'll need some help to become the FedEx Cup champion and get the $US10 million ($A10.75 million) bonus it comes with.

He would need to firstly win the event and then hope the top five guys aren't close on his heels. No.1 seed Tiger Woods would have to be tied eighth or worse, No.2 Henrik Stenson tied fourth or worse, No.3 Adam Scott tied third or worse, No.4 seed Zach Johnson in a three way tie for second or worse and No.5 seed Matt Kuchar tied second or worse for Day to win the lot.

"I am just happy to be here and have a chance," Day said.

"I am in a can't lose situation at 14th where all I can do is control what I do.

"All I am focused on is doing the best job I can and hopefully that job is finishing one at the end of the week."